Cor Vasa 2004, 45(11):544-551

Functional mitral regurgitation

Richard Fojt*, Rudolf ©paček, Filip Málek, Jiří Krupička
III. interní-kardiologická klinika, Kardiocentrum, Fakultní nemocnice Královské Vinohrady a 3. lékařská fakulta Univerzity Karlovy, Praha, Česká republika

This review article summarizes the evolution of our understanding of the natural history, incidence, and significance of functional mitral regurgitation in myocardial infarction survivors. Individual mechanisms resulting in the development of functional mitral regurgitation, particularly changes of left ventricular geometry, mitral annulus dilatation, and papillary muscle dysfunction, are discussed in detail. According to the most recent concepts, a combination of these individual fac-tors results in an incomplete closure of the mitral valve leaflets and in the formation of a so-called regurgitation orifice. The relationship of functional mitral regurgitation with individual manifestations of myocardial infarction is discussed sepa-rately and related especially to the localization of myocardial infarction and the remodeling process following myocardial infarction.

Keywords: Functional mitral regurgitation; Myocardial infarction; Remodeling; Papillary muscles

Published: November 1, 2004  Show citation

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Fojt R, ©paček R, Málek F, Krupička J. Functional mitral regurgitation. Cor Vasa. 2004;45(11):544-551.
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