Cor Vasa 2026, 68(3):314-319

(Some diagnostic markers of heart failure in patients with aortic valve stenosis)

David Čmejreka, Martin Hudecb, Mária Ivančíkováb, Peter Fleischerc
a Oddelenie funkčnej diagnostiky, Stredoslovenský ústav srdcových a cievnych chorôb, Banská Bystrica, Slovensko
b Oddelenie akútnej kardiológie, Stredoslovenský ústav srdcových a cievnych chorôb, Banská Bystrica, Slovensko
c Katedra integrovanej ochrany lesa a krajiny, Lesnícka fakulta, Technická univerzita vo Zvolene, Zvolen, Slovensko

Aortic valve stenosis is the most common valvular heart disease in adults. This valve defect often coexists with heart failure syndrome. In our study, we retrospectively analyzed data from 121 patients hospitalized at SUSCCH between March 2024 and March 2025. We examined the dependence of NTproBNP values and their correlation with echocardiographic parameters - LV mass, E/e´, LAVi, LV EF, and PGmean. In our cohort, NTproBNP as a diagnostic marker of heart failure in the context of severe aortic valve stenosis proved to be of little diagnostic value in the initial and mildly advanced stages, with its significance increasing only in the advanced stage of the disease associated with LV remodeling and a decrease in LVEF. Echocardiographic indicators (LV mass, LAVi, and E/e´) may aid in risk stratification and planning the timing of intervention. However, these observations require confirmation in multivariate and prospective analyses.

Keywords: Aortic valve stenosis, Echocardiography, Heart failure, NTproBNP

Received: November 3, 2025; Revised: November 18, 2025; Accepted: December 7, 2025; Prepublished online: June 2, 2012; Published: July 1, 2026  Show citation

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Čmejrek D, Hudec M, Ivančíková M, Fleischer P. (Some diagnostic markers of heart failure in patients with aortic valve stenosis). Cor Vasa. 2026;68(3):314-319.
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