Cor Vasa 2026, 68(4):410-417 | DOI: 10.33678/cor.2026.011

Účinnost psychologických intervencí v léčbě arteriální hypertenze: přehledová studie.

Radka Kozáková, Radka Bužgová, Katka Bobčíková, Hana Hanyášová, Renáta Zeleníková
Ústav ošetřovatelství a porodní asistence, Lékařská fakulta, Ostravská univerzita, Ostrava, Česká republika

Aim: The aim of this narrative review was to evaluate the effectiveness of psychological interventions in the treatment of arterial hypertension, with a particular focus on their impact on blood pressure, psychological outcomes (stress, anxiety, depression), and quality of life.

Methods: Randomized controlled trials published between 2015 and 2025 were identified through searches of PubMed, ScienceDirect, and the Cochrane Library. Studies evaluating cognitive behavioral therapy (CBT), mindfulness-based interventions, relaxation techniques, and stress management programs were included. Methodological quality was assessed using the PEDro scale.

Results: A total of 17 RCTs were included in the review. Most studies reported a statistically significant reduction in systolic blood pressure, particularly in interventions based on CBT and mindfulness. CBT demonstrated the most robust long-term effects on blood pressure reduction, treatment adherence, and quality of life. Mindfulness-based interventions were consistently associated with reductions in perceived stress, anxiety, and depressive symptoms, as well as favorable changes in biological markers of inflammation. Relaxation techniques produced rapid physiological effects, which were most pronounced when combined with cognitive-behavioral approaches.

Conclusion: Psychological interventions represent an effective and clinically relevant adjunct to standard hypertension management. Their integration into comprehensive care may improve blood pressure control, psychological well-being, and overall quality of life in patients with arterial hypertension. © 2026, ČKS.

Keywords: Hypertension, Non-pharmacological therapy, Psychological intervention, Quality of life

Received: January 5, 2026; Revised: February 3, 2026; Accepted: February 4, 2026; Prepublished online: August 5, 2026; Published: August 31, 2026  Show citation

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Kozáková R, Bužgová R, Bobčíková K, Hanyášová H, Zeleníková R. Účinnost psychologických intervencí v léčbě arteriální hypertenze: přehledová studie. Cor Vasa. 2026;68(4):410-417. doi: 10.33678/cor.2026.011.
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    References

    1. Townsend N, Kazakiewicz D, Lucy Wright F, et al. Epidemiology of cardiovascular disease in Europe. Nat Rev Cardiol 2022;19:133-143. Go to original source...
    2. Gaidai O, Cao Y, Loginov S. Global cardiovascular diseases death rate prediction. Curr Probl Cardiol 2023;48:101622. Go to original source...
    3. WHO. Hypertension. World Health Organization 2025. Online. Dostupné z: https://www.who.int/news-room/fact-sheets/ detail/hypertension. [citováno 2026-08-05].
    4. Amlak BT, Getie A, Messelu MA, et al. Health-related quality of life among adult hypertensive patients globally: a systematic review and meta-analysis. BMJ Public Health 2025;3:e001662. Go to original source... Go to PubMed...
    5. Elsaid N, Saied A, Kandil H, et al. Impact of stress and hypertension on the cerebrovasculature. Front Biosci (Landmark Ed) 2021;26:1643-1652. Go to original source...
    6. Walther LM, Wirtz PH. Physiological reactivity to acute mental stress in essential hypertension - a systematic review. Front Cardiovasc Med 2023;10:1215710. 416 Účinnost psychologických intervencí v léčbě arteriální hypertenze Go to original source...
    7. Zou C, Chen H, Liu C, et al. Non-pharmacological and psychosocial interventions for comorbid hypertension and depression: a scoping review. BMJ Open 2025;15:e096928. Go to original source...
    8. Araya R, Menezes PR, Claro HG, et al. Effect of a Digital Intervention on Depressive Symptoms in Patients With Comorbid Hypertension or Diabetes in Brazil and Peru: Two Randomized Clinical Trials. JAMA 2021;325:1852-1862. Go to original source...
    9. Chen D. Effect of Health Qigong Mawangdui Daoyinshu on Blood Pressure of Individuals with Essential Hypertension. J Am Geriatr Soc 2016;64:1513-1515. Go to original source...
    10. Wang L, Liu Q, Sun D, et al. Effects of Combination Treatment in Hypertensive Patients with Depression: A Systematic Review and Meta-Analysis of 27 Randomized Controlled Trials. Ther Clin Risk Manag 2022;8:197-211. Go to original source...
    11. Ahmadpanah M, Paghale SJ, Bakhtyari A, et al. Effects of psychotherapy in combination with pharmacotherapy, when compared to pharmacotherapy only on blood pressure, depression, and anxiety in female patients with hypertension. J Health Psychol 2016;21:1216-1227. Go to original source... Go to PubMed...
    12. Webster KE, Halicka M, Bowater RJ, et al. Effectiveness of stress management and relaxation interventions for management of hypertension and prehypertension: systematic review and network meta-analysis. BMJ Medicine 2025;4:e001098. Go to original source... Go to PubMed...
    13. Maher CG, Sherrington C, Herbert RD, et al. Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther 2003;83:713-721. Go to original source...
    14. de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother 2009;55:129-133. Go to original source... Go to PubMed...
    15. Nejati S, Zahiroddin A, Afrookhteh G, et al. Effect of group mindfulness-based stress-reduction program and conscious yoga on lifestyle, coping strategies, and systolic and diastolic blood pressures in patients with hypertension. J Tehran Heart Cent 2015;10:140-148.
    16. Dou XT, Ji MJ, Sun ZY, et al. The impact of psychological factors on hypertension and its psychological intervention in pilot selection candidates. Front Psychol 2025;16: 1634423. Go to original source...
    17. Liu L, Li M, Song S, et al. Effects of long-term psychological intervention on blood pressure and health-related quality of life in patients with hypertension among the Chinese working population. Hypertens Res 2017;40:999-1007. Go to original source... Go to PubMed...
    18. Babak A, Motamedi N, Mousavi SZ, et al. Effects of Mindfulness-Based Stress Reduction on Blood Pressure, Mental Health, and Quality of Life in Hypertensive Adult Women: A Randomized Clinical Trial Study. J Tehran Heart Cent 2022;17:127-133. Go to original source...
    19. Birashk B, Sheybani F, Gharraee B, et al. Comparison effectiveness of MBSR and CBT on interleukin 6 and oxidative stress in hypertensive patients. Int J Life Sci Pharma Res 2018;8:(L)39-45.
    20. Kumar S, Lathif F, Raghavan V. Effects of Mindfulness-Based Stress Reduction on Blood Pressure (MBSR) Among Patients with Type-2 Diabetes - A Randomised Pilot Study. Nurs J India 2017;108:61-63. Go to original source...
    21. Loucks EB, Schuman-Olivier Z, Saadeh FB, et al. Effect of Adapted Mindfulness Training in Participants With Elevated Office Blood Pressure: The MB-BP Study: A Randomized Clinical Trial. J Am Heart Assoc 2023;12:e028712. Go to original source... Go to PubMed...
    22. Momeni J, Omidi A, Raygan F, et al. The effects of mindfulness-based stress reduction on cardiac patients' blood pressure, perceived stress, and anger: a single-blind randomized controlled trial. J Am Soc Hypertens 2016;10:763- Go to original source...
    23. Ponte Márquez PH, Feliu-Soler A, Solé-Villa MJ, et al. Benefits of mindfulness meditation in reducing blood pressure and stress in patients with arterial hypertension. J Hum Hypertens 2019;33:237-247. Go to original source...
    24. Zhang H, Zhang X, Jiang X, et al. Mindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial. Trials 2024;25:299. Go to original source...
    25. Clemow LP, Pickering TG, Davidson KW, et al. Stress management in the workplace for employees with hypertension: a randomized controlled trial. Transl Behav Med 2018;8:761-770. Go to original source...
    26. Lindsay EK, Young S, Smyth JM, et al. Acceptance lowers stress reactivity: Dismantling mindfulness training in a randomized controlled trial. Psychoneuroendocrinology 2018;87:63-73. Go to original source... Go to PubMed...
    27. Nolan RP, Feldman R, Dawes M, et al. Randomized controlled trial of E-Counseling for hypertension. Circulation: Cardiovasc Qual Outcomes 2018;11:e004420. Go to original source...
    28. Tanaka R, Nolan RP. Psychobehavioral profiles to assist tailoring of interventions for patients with hypertension: Latent profile analysis. J Med Internet Res 2018;20:e149. Go to original source...
    29. Mensorio MS, Cebolla-Martí A, Rodilla E, et al. Analysis of the efficacy of an internet-based self-administered intervention ("Living Better") to promote healthy habits in a population with obesity and hypertension: An exploratory randomized controlled trial. Int J Med Inform 2019;124:13-23. Go to original source...
    30. Pathan FKM, Pandian JS, Shaikh AI, et al. Effect of slow breathing exercise and progressive muscle relaxation technique in the individual with essential hypertension: A randomized controlled trial. Medicine (Baltimore) 2023;102:e35792. Go to original source...
    31. Cohen DL, Boudhar S, Bowler A, et al. Blood Pressure Effects of Yoga, Alone or in Combination With Lifestyle Measures: Results of the Lifestyle Modification and Blood Pressure Study (LIMBS). J Clin Hypertens 2016;18:809-816. Go to original source...
    32. Unger T, Borghi C, Charchar F, et al. International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension 2020;75:1334-1357. Go to original source...
    33. Ginty AT, Carroll D, Roseboom TJ, et al. Depression and anxiety are associated with a diagnosis of hypertension 5 years later in a cohort of late middle-aged men and women. J Hum Hypertens 2013;27:187-190. Go to original source... Go to PubMed...
    34. Mancia G, Kreutz R, Brunström M, et al. ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA). J Hypertens 2023;41:1874-2071. Go to original source...
    35. Writing Committee Members; Jones DW, Ferdinand KC, et al. AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/ NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Hypertension 2025;82:e212-e316.
    36. Creswell JD, Lindsay EK, Villalba DK, Chin B. Mindfulness Training and Physical Health: Mechanisms and Outcomes. Psychosom Med 2019;81:224-232. Go to original source...
    37. Schaeuffele C, Meine LE, Schulz A, et al. A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders. Nat Hum Behav 2024;8:493- Go to original source...
    38. Liu J, Gill NS, Teodorczuk A, et al. The efficacy of cognitive behavioural therapy in somatoform disorders and medically unexplained physical symptoms: A meta-analysis of randomized controlled trials. J Affect Disord 2019;245:98-112. Go to original source... Go to PubMed...
    39. Xue F, Yao W, Lewin RJ. A randomised trial of a 5 week, manual based, self-management programme for hypertension delivered in a cardiac patient club in Shanghai. BMC Cardiovasc Disord 2008;8:10. Go to original source...
    40. Israfil I, Yusuf A, Efendi F. Effect of Cognitive Behavioral Therapy on The Behavior of Patients with Cardiovascular Disease: A Systematic Review. Gaceta Medica de Caracas. 2023;131:S478-S488. Go to original source...
    41. Burnier M. Managing 'resistance': is adherence a target for treatment? Curr Opin Nephrol Hypertens 2014;23:439-443. Go to original source...
    42. De Geest S, Ruppar T, Berben L, et al. Medication nonadherence as a critical factor in the management of presumed resistant hypertension: a narrative review. EuroIntervention 2014;9:1102-1109. Go to original source...
    43. Wolgensinger L. Cognitive behavioral group therapy for anxiety: recent developments. Dialogues Clin Neurosci 2015;17:347-351. Go to original source...
    44. Asyari H, Rohaedi S, Marsono M, et al. Effect of deep breathing relaxation and progressive muscle relaxation on R. Kozáková et al.417 blood pressure. Jurnal Penelitian Pendidikan IPA 2024;10:2565- 2571. Go to original source...
    45. Calderone A, Marafioti G, Latella D, et al. Effectiveness of relaxation techniques for stress management and quality of life improvement in cardiovascular disease and hypertensive patients: a systematic review. Psychol Health Med 2025;30:1281-1352. Go to original source...
    46. Blumenthal JA, Sherwood A, Smith PJ, et al. Enhancing cardiac rehabilitation with stress management training: A randomized, clinical efficacy trial. Circulation 2016;133:1341-1350. Go to original source...
    47. Lee EKP, Yeung NCY, Xu Z, et al. Effect and acceptability of mindfulness-based stress reduction program on patients with elevated blood pressure or hypertension: a Meta-analysis of randomized controlled trials. Hypertension 2020;76: 1992-2001 Go to original source...
    48. Conversano C, Orru G, Pozza A, et al. Is mindfulness-based stress reduction effective for people with hypertension? A systematic review and Meta-analysis of 30 years of evidence. Int J Environ Res Public Health 2021;18:2872. Go to original source... Go to PubMed...
    49. Chen Q, Liu H, Du S. Effect of mindfulness-based interventions on people with prehypertension or hypertension: a systematic review and meta-analysis of randomized controlled trials. BMC Cardiovasc Disord 2024;24:104. Go to original source... Go to PubMed...
    50. Mikolasek M, Berg J, Witt CM, et al. Effectiveness of mindfulness- and relaxation-based eHealth interventions for patients with medical conditions: a systematic review and synthesis. Int J Behav Med 2018;25:1-16. Go to original source...
    51. Rogers JM, Ferrari M, Mosely K, et al. Mindfulness-based interventions for adults who are overweight or obese: a metaanalysis of physical and psychological health outcomes. Obes Rev 2017;18:51-67. Go to original source...

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