Cor et Vasa - Latest articles
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Kapesní verze Doporučení ESC /EACTS pro léčbu chlopenních vad 2025. Praz F, Borger MA, Lanz J, Marin-Cuartas M, Abreu A, Adamo M, Marsan NA, Barili F, Bonaros N, Cosyns B, De Paulis R, Gamra H, Jahangiri M, Jeppsson A, Klautz RJM, Mores B, Pérez-David E, Pöss J, Prendergast BD, Rocca B, Rossello X, Suzuki M, Thiele H, Tribouilloy CM, Wojakowski W. Překlad vypracovaný Pracovní skupinou chlopenní a vrozené srdeční vady v dospělosti České kardiologické společnostiGuidelines
Hana Línkováa, Martin Matesb, Petr Toušekc, Zuzana Hlubockád, Tomáš Palečekd, Marian Brannye
Cor Vasa 2026, 68(Suppl.1):39-71 | DOI: 10.33678/cor.2026.038 
2025 cílená aktualizace doporučení ESC/EAS z roku 2019 pro léčbu dyslipidemiíGuidelines
Mach F, Koskinas KC, Roeters van Lennep JE, Tokgözoğlu L, Badimon L, Baigent C, Benn M, Binder CJ, Catapano AL, De Backer GG, Delgado V, Fabin N, Ference BA, Graham IM, Landmesser U, Laufs U, Mihaylova B, Nordestgaard BG, Richter DJ, Sabatine MS, Michal Vrablík, Martin Šatný, Miloš Táborský
Cor Vasa 2026, 68(Suppl.1):30-38 | DOI: 10.33678/cor.2026.032
Kapesní verze konsenzuálního dokumentu ESC pro klinickou praxi. Konsenzuální dokument ESC ke vztahu duševního zdraví a kardiovaskulárních onemocnění v klinické praxi 2025Guidelines
Bueno H, Deaton C, Farrero M, Forsyth F, Braunschweig F, Buccheri S, Dragan S, Gevaert S, Held C, Kurpas D, Ladwig KH, Lionis CD, Maas AHEM, Merșa CO, Mindham R, Pedersen SS, Kuzman MR, Szmit S, Taylor RS, Uchmanowicz I, Vilchinsky N, Bueno H, Deaton C, Farrero M, Forsyth F, Braunschweig F, Buccheri S, Dragan S, Gevaert S, Held C, Kurpas D, Ladwig KH, Lionis CD, Maas AHEM, Merșa CO, Mindham R, Pedersen SS, Kuzman MR, Szmit S, Taylor RS, Uchmanowicz I, Vilchinsky N, Miloš Táborský, Aleš Linhart, Michal Vrablík
Cor Vasa 2026, 68(Suppl.1):4-29 | DOI: 10.33678/cor.2026.030
Profesor MUDr. Jan Janoušek, Ph.D., sedmdesátiletýPersonalia
Prof. MUDr. Jan Marek, Ph.D., FESC
Cor Vasa 2026, 68(2):247-248 | DOI: 10.33678/cor.2026.020
Jubileum profesora Jana ČernéhoPersonalia
Michael Aschermann
Cor Vasa 2026, 68(2):246 | DOI: 10.33678/cor.2026.048
Prof. MUDr. Jan Černý, CSc., již 85letýPersonalia
Petr Němec, Petr Fila
Cor Vasa 2026, 68(2):245-246 | DOI: 10.33678/cor.2026.047
Paní profesorka Iveta Šimková se dožívá životního jubileaPersonalia
Michael Aschermann
Cor Vasa 2026, 68(2):244 | DOI: 10.33678/cor.2026.046
Za MUDr. Marií Voříškovou, jednou z klíčových osobností české dětské kardiologiePersonalities
Prof. MUDr. Jan Janoušek, Ph.D.
Cor Vasa 2026, 68(2):242-243 | DOI: 10.33678/cor.2026.041
Odešel profesor Eugene Braunwald – gigant světové kardiologiePersonalities
Prof. MUDr. Petr Widimský, DrSc., FESC
Cor Vasa 2026, 68(2):240-241 | DOI: 10.33678/cor.2026.040
(Abnormal electrocardiogram findings in athletes. A consensus statement of the European Association of Preventive Cardiology of the European Society of Cardiology. Translation prepared by the Sports Cardiology Section of the Czech Association of Preventive Cardiology of CKS)Expert consensus statement
Eliška Sovová, Libor Jelínek, Jiří Pařenica, Bogna Jiravská-Godula, Otakar Jiravský, Vladimír Tuka
Cor Vasa 2026, 68(2):224-238 | DOI: 10.33678/cor.2025.138
Athletes commonly exhibit a series of electrical, structural, and functional physiological changes which may overlap with cardiac pathology. The last two decades have witnessed a progressive improvement in understanding what can be considered benign for athletes and what may be deemed as potentially pathological and require further investigations. However, diagnostic uncertainties in the cardiac assessment of athletes are often encountered. In particular, the clinical significance of some electrocardiogram (ECG) findings may be uncertain. While uncommon and suggestive of an underlying cardiac condition, they may be identified among healthy athletes...
Prenatální kardiologie. Sdílená doporučení České kardiologické společnosti (ČKS) a České gynekologické a porodnické společnosti České lékařské společnosti Jana Evangelisty Purkyně (ČGPS ČLS JEP)Guidelines
Jan Marek, Radovan Vlk, Viktor Tomek, Patrik Šimják, Hana Jičínská, Eva Klásková, Vladimír Dvořák
Cor Vasa 2026, 68(2):212-223 | DOI: 10.33678/cor.2026.021
Selection of Oral Anticoagulants in Atrial Fibrillation Patients Based on SAMe-TT2R2 ScoreReview articles
Lutfu Askin, Kazim Ersin Altinsoy, Irfan Yaman, Veysel Ozgur Baris, Okan Tanriverdi
Cor Vasa 2026, 68(2):206-211 | DOI: 10.33678/cor.2025.097
Clinicians must select between vitamin K antagonists (VKA) like warfarin and non-VKA oral anticoagulants for atrial fibrillation patients. According to observational studies, VKA patients have had international normalised ratio (INR) values outside the time in therapeutic range (TTR < 60%) for a long period of time. Based on common clinical criteria, the SAMe-TT2R2 score may help evaluate whether a VKA will work for a patient. SAMe-TT2R2 scores of 0-1 should perform well on a VKA, whereas values of 2 may result in inadequate TTR. We will examine how consistent the SAMe-TT2R2 score is in selecting oral anticoagulants for atrial fibrilla- tion patients...
Cardiovascular Bypass Surgery: Contemporary Strategies for Postoperative Cardiac Follow-UpReview articles
Gökhan Ceyhun
Cor Vasa 2026, 68(2):201-205 | DOI: 10.33678/cor.2025.128
Coronary artery bypass grafting (CABG) remains the cornerstone surgical therapy for complex or advanced coronary artery disease. Yet, the long-term success of CABG depends heavily on systematic postoperative cardiac follow-up. Early evaluation focuses on arrhythmia prevention, hemodynamic stability, and detection of perioperative myocardial injury, whereas long-term care integrates graft surveillance, risk-factor modification, and rehabilitation. New data highlight biomarkers such as NT-proBNP, galectin-3, and adropin, together with imaging modalities like strain echocardiography and cardiac CT angiography. A multidisciplinary, patient-centered model...
(The Current Role of Diuretic Therapy in the Treatment of Heart Failure)Review articles
Jan Mikula
Cor Vasa 2026, 68(2):196-200 | DOI: 10.33678/cor.2025.103
Diuretic therapy, particularly with loop diuretics, represents a cornerstone of pharmacological management in patients with symptomatic heart failure. This review article summarizes the effects of diuretic therapy on the cardiovascular system, outlines current clinical recommendations, and discusses the available evidence supporting the use of loop diuretics in both acute and chronic heart failure.
Betablokátory v sekundární prevenci infarktu myokardu - poznatky z nových klinických studiíReview articles
Petr Janský
Cor Vasa 2026, 68(2):189-194 | DOI: 10.33678/cor.2026.042
Beta-blockers have been used in the secondary prevention of myocardial infarction for more than forty years. A number of historical clinical studies have demonstrated a significant reduction in both mortality and morbidity when they are administered. The positive effects of beta-blockers are most pronounced in patients with left ventricular systolic dysfunction or with symptoms of heart failure. In the past two years, the results of several large randomized prospective studies have been published, clarifying the role of beta-blockers even in patients after myocardial infarction with mildly reduced or preserved left ventricular ejection fraction. While...
Techniques for dose reduction in pediatric cardiac CTReview articles
Marek Kardoš
Cor Vasa 2026, 68(2):179-187 | DOI: 10.33678/cor.2025.127
The increased use of CT scans in children over the past decades has raised concerns about the long-term risks of radiation exposure from diagnostic imaging. Children are more vulnerable to the harmful effects of radiation because they have a longer lifespan, allowing more time for radiation-related effects to accumulate. Technological innovations in computed tomography have facilitated significant reductions in radiation exposure for both adult and pediatric patients while preserving diagnostic imaging quality.
Combined vitamin K2, vitexin, and vitamin D3 (K2VD3) intake in patients with peripheral artery diseaseOriginal research articles
Gianluigi Rosi, Daniele Ceccaroni, Daniela Fruttini
Cor Vasa 2026, 68(2):173-178 | DOI: 10.33678/cor.2025.102
Objective: This observational study investigates therapeutic efficacy of bioactive compounds (vitexin, vitamin K2, and vitamin D3, K2VD3) in alleviating claudicatio intermittens in patients with peripheral artery disease (PAD). Methods: Patients with PAD stage IIb under best medical cure were treated with life-style therapy and K2VD3 for 12 months. Results: Mean pain-free walking distance, described at baseline as 123 meters (95% CI 17-297), increase as follow: 376 (95% CI 226-527), 794 (95% CI 517-1070), 2 645 (95% CI 1511-3780), and 2 659 (95% CI 1529-3789) meters after 2, 4, 6 and 12 months, respectively (p < 0.001 for each...
Clinical predictors of appropriate electrical storm in patients with implantable cardioverter defibrillatorOriginal research articles
Nawar A. Hamed, Ali Abdul-Ameer Al Mousawi, Kasim Abbas Ismail Al-Iqabby, Adil Hassan Al-Husseiny
Cor Vasa 2026, 68(2):166-172 | DOI: 10.33678/cor.2025.133
Background: Appropriate electrical storm (ES) in patients with implantable cardioverter-defi brillators (ICDs) is a life-threatening condition characterized by recurrent, appropriate ICD therapies; antitachycardia pacing (ATP) and/or shocks; within a 24-hour period. Some authors defi ne ES as three or more VT/VF episodes separated by at least 5 minutes of sinus rhythm. ICD shocks have signifi cant adverse effects, and available evidence indicates that patients experiencing ES have poorer outcomes. Potential triggers include changes in or non-adherence to medication, worsening heart failure, early postoperative states, emotional stress, alcohol...
Coronary Flow Velocity Reserve in Subjects with High HDL CholesterolOriginal research articles
Ozge Telci Caklili, Fatma Betul Ozcan, Ramazan Cakmak, Tugce Irgi, Oguz Konal, Mustafa Caliskan
Cor Vasa 2026, 68(2):161-165 | DOI: 10.33678/cor.2025.100
Background: In recent years, it has been debated whether high HDL-C definitely provides cardiovascular protection. We compared coronary flow velocity reserve (CFVR) of subjects with normal HDL-C levels with subjects who have high HDL-C levels.Methods and results: Subjects who were evaluated for angina with no pathological findings at the Cardiology Department of Istanbul Medeniyet University between 2012–2022 were screened and included to analysis if their HDL-C levels were ≥ 50 mg/dL. They were divided into two groups: (1) patients with HDL-C ≥ 70 mg/dL and (2) patients with HDL-C ≥ 50 and < 70 mg/ dL. Groups were...
Clinical Presentation of Cardiac Myxoma at Tertiary Referral Hospital in East IndonesiaOriginal research articles
Yan Efrata Sembiring, Muhammad Husein Dzikrillah, Ali Mustofa, Oky Revianto Sediono Pribadi, Danang Himawan Limanto, Edwin Yosef Widjaja, Heroe Soebroto, Jeffrey Jeswant Dillon, Pandit Bagus Tri Saputra
Cor Vasa 2026, 68(2):157-160 | DOI: 10.33678/cor.2025.095
Introduction: Cardiac myxoma is the most common benign cardiac tumor. Despite global data availability, there is a lack of published literature on its clinical characteristics in Indonesia. This study aims to describe the clinical presentation and surgical outcomes of cardiac myxoma cases treated at a tertiary referral hospital in East Indonesia. Methods: A retrospective review was conducted on patients who underwent surgical resection for cardiac myxoma between January 2020 and August 2024. Clinical data including demographics, symptoms, tumor characteristics, diagnostic methods, and surgical outcomes were analyzed descriptively. Results:...
Association of Triglyceride-Glucose Index and Its Derived Parameters with Metabolic Syndrome in Indonesian Police Officers: A Cross-Sectional StudyOriginal research articles
Yusuf Aji Samudera Nurrobi, Chabib Fachry Albab, Ken Christian Kawilarang, Meity Ardiana
Cor Vasa 2026, 68(2):150-156 | DOI: 10.33678/cor.2025.092
Background: The triglyceride-glucose (TyG) index and its derivatives, TyG-BMI, TyG-WC, and TyG-WHtR, have been linked to metabolic syndrome (MetS) in a number of populations and are known to be surrogate markers for insulin resistance. Their association value, however, can change among various racial and vocational groups. Objective: To assess the relationship between metabolic syndrome and the triglyceride-glucose index and its related characteristics in Indonesian police officers. Methods: 3,600 Indonesian police personnel between the ages of 33 and 70 were evaluated in this cross-sectional study (3,201 men and 399 women). The TyG index...
Study of the Effect of Telecommunication Follow-Up for Patients on Warfarin During the COVID-19 PandemicOriginal research articles
Mohamed A. Abdelwahab, Karim Kamal, Mohamed El-Ramly, Kareem Mahmoud
Cor Vasa 2026, 68(2):143-149 | DOI: 10.33678/cor.2025.094
Background: Warfarin, a vitamin K antagonist oral anticoagulant, requires frequent monitoring of the international normalized ratio (INR). Telemedicine has emerged as a crucial tool for facilitating remote health- care access, particularly during the COVID-19 pandemic. However, the efficacy and safety of this model for managing warfarin patients in Egypt remain unexplored. Aim: This study compared telemedicine with conventional warfarin clinic visits regarding achieving target INR and time in therapeutic range (TTR), while assessing differences in expenses and complications. Methods: Patients receiving warfarin at two tertiary centers in Egypt were...
(Assessment of the possible impact of COVID-19 infection on the autonomic nervous system in the pediatric population)Original research articles
Martina Šišáková, Kateřina Helánová, Irena Andršová, Tomáš Novotný, Jiří Pařenica, Lukáš Homola, Martin Sihlovec
Cor Vasa 2026, 68(2):137-142 | DOI: 10.33678/cor.2025.107
Objective: Autonomic changes, such as increased sympathetic manifestations, are a common complication of acute viral infections. Our study considered the possibility that SARS-CoV-2 infection leads to long-term abnormalities of the autonomic nervous system that persist even after the acute and subacute phases of the infection have resolved. The aim of this study was to assess the effect of COVID-19 infection on autonomic nervous system modulation in children. Methods: A total of 165 children (89 girls) 6.7 to 18.6 year old were enrolled. Each participant underwent a postural provocation test (supine and standing positions) during which ECG recording...
Michael Aschermann, Ondřej Aschermann: Historie katetrizací srdceBook reviews
Prof. MUDr. Tomáš Kovárník, Ph.D.
Cor Vasa 2026, 68(1):127-128 | DOI: 10.33678/cor.2026.004
Internista a kardiolog profesor Richard Češka se stal šéfem světové interní medicínyCurrent news
Michael Aschermann
Cor Vasa 2026, 68(1):126 | DOI: 10.33678/cor.2026.009
Pan profesor MUDr. Jiří Vítovec, CSc., FESC, slaví životní jubileumPersonalia
Michael Aschermann
Cor Vasa 2026, 68(1):125 | DOI: 10.33678/cor.2026.008
Zemřel dětský kardiolog a intenzivista primář MUDr. Jaroslav Wiedermann, CSc. (6. 4. 1949–4. 12. 2025)Personalities
Prof. MUDr. Eva Klásková, Ph.D., MHA; MUDr. Sabina Kaprálová, Ph.D.; MUDr. Alžběta Palátová
Cor Vasa 2026, 68(1):124 | DOI: 10.33678/cor.2026.010
Opustil nás profesor Jan Petrášek (8. 9. 1929–12. 2. 2026)Personalities
Michael Aschermann
Cor Vasa 2026, 68(1):123 | DOI: 10.33678/cor.2026.015
Relationship of Neutrophil-Lymphocyte Ratio (NLR) as Diagnostics and Prognostics Tools of Deep Vein Thrombosis (DVT): Current StatusReview articles
Zanella Yolanda Lie, Yan Efrata Sembiring
Cor Vasa 2026, 68(1):119-122 | DOI: 10.33678/cor.2025.081
The neutrophil-lymphocyte ratio (NLR) has emerged as a promising biomarker in deep vein thrombosis (DVT), reflecting the intricate relationship between inflammation and thrombosis. This literature review examines NLR's dual role as both a diagnostic and prognostic tool in DVT management. Current evidence demonstrates that elevated NLR (>3.0) correlates strongly with DVT occurrence, severity, and recurrence risk, particularly in high-risk populations such as postoperative and cancer patients. Mechanistically, NLR captures the pro-thrombotic effects of neutrophil extracellular traps (NETs) and the anti-thrombotic regulation by lymphocytes, offering...
Klippel-Trénaunay syndrome: the etiology, clinical presentation, and treatment optionsReview articles
Mária Rašiová, Martin Koščo, Marek Hudák, Veronika Pavlíková, Adriana Rašiová, Marta Bavoľárová
Cor Vasa 2026, 68(1):111-118 | DOI: 10.33678/cor.2025.106
Objective: Klippel-Trénaunay syndrome (KTS) is a combined slow-flow vascular malformation associated with excessive growth of limbs. The aim of this review is to summarize the knowledge about the presumed etiology, the most common anomalies associated with KTS, the diagnostic approach, and the treatment strategies. Methods: A literature search was conducted between January and May 2025 using PubMed and Google Scholar databases, focusing on terms such as Klippel-Trénaunay syndrome and PIK3CA-related overgrowth spectrum (PROS). Conclusions: KTS manifests as a cluster of congenital malformations affecting the limb and typically affects the lower...